DMEM is a modification of Basal Medium Eagle (BME) that contains four-fold concentration of amino acids and vitamins. Dulbecco's Modified Eagle Medium contains L-glutamine, 1gm glucose per litre, sodium bicarbonate and sodium pyruvate. It does not contain Phenol red. Dulbecco's Modified Eagle Medium (DMEM) is one of the most widely used modifications of Eagles medium. DMEM is a modification of Basal Medium Eagle (BME) that contains four fold concentration of amino acids and vitamins. Additionally, the formulation also includes glycine, serine and ferric nitrate. The original formulation contains 1000mgs/L of Glucose and was originally used to culture embryonic mouse cells. AL183A is Dulbecco's Modified Eagle Medium and contains L glutamine, 1gm glucose per litre, sodium bicarbonate and sodium pyruvate. It does not contain Phenol red.