Human Recombinant mucin Source : CHO cells Cell Culture Tested

CF064 is a recombinant human recombinant mucin expressed in CHO cells as optimized DNA sequence encoding encoding Human Mucin (32 - 168AA) including a C-terminal His tag. It has been filtered through 0.2μ membrane filter and lyophilized from PBS solution, pH 7.2, 5% Trehalose. Mucins are high molecular weight glycoproteins consisting of 80% carbohydrates and 20% core protein. This glycoprotein line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from bouts of infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 protein is associated with colon, breast, ovarian, lung and pancreatic cancers. Whereas, decreased levels may indicate positive response to cancer treatment.