TOC Agar is recommended for the presumptive identification and differentiation of Candida albicans and Cryptococcus neoformans. It is a multi-purpose medium developed by Fleming et al (2) for the rapid,presumptive identification of C. albicans and C. neoformans. A combination of sorbitan monooleate 80 and oxbile promotes their rapid, sequential development. C. neoformans may be identified by the production of a characteristic brown pigment on this medium.